PLA2- Phosopholipase A2

  • Front view of the Phosopholipase A2 Sculpture
  • Wire model of Phosopholipase A2 on which the Sculpture was based
  • Close-up of the Phosopholipase A2 Sculpture
  • Back view of the Phosopholipase A2 Sculpture
  • Front view of the Phosopholipase A2 Sculpture showing transitions state analog
Phosopholipase A2

Pancreatic phospholipase A2 is a pancreatic enzyme that releases fatty acids from the second carbon group of glycerol triesters. The sculpture shows the enzyme with a transition state analog bound to it. The model is made of brass and stainless steel and mounted on a maple base. The piece was commissioned by Professor E.A. Dennis at University of California, San Diego, who for many years has studied this enzyme and its congeners.

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