Fibroblast Growth Factor

The fibroblast growth factor (FGF) family members possess broad mitogenic and cell survival activities. They are involved in a variety of biological processes, including embryonic development, ructurenof cell growth, morphogenesis, tissue repair, tumor growth and invasion. Structurally, the members of the FGF family are all similar. Functionally, they act as a modifiers of endothelial cell migration and proliferation, as well as angiogenic factors. The sculpture of FGF is based upon the structure of FGF1, acidic FGF, and shows the pseudo-three fold symmetry characteristic of this family of growth factors. The sculpture made of gold-plated stainless steel and stands approximately 13 inches above a black granite base.