Byetta
A model of exentide-4 (Byetta) based upon the NMR structure of a related peptide GLP-1.
Dihydrofolate Reductase with Methotrexate
Mammalian dihydrofolate reductase (DHFR) is a key target for treating forms of cancer.
DNA
As part of the redesign of the lobby at Serono’s Rockland, MA site, three strands of DNA commissioned to high-light its mezzanine.
Dipeptidyl Protease IV with Januvia
Dipeptidylpotease IV (DPPIV)is an enzyme known to hydrolyze glucagon-like peptide-1 (GLP-1) in the human gut.
Fibroblast Growth Factor
The fibroblast growth factor (FGF) family members possess broad mitogenic and cell survival activities.
Follicle Stimulating Hormone
Follicle stimulating hormone is a two subunit protein hormone marketed by Serono to enhance fertility.
Human Fibroblast Collagenase
Human fibroblast collagenase, HFC, is one of a number of matrix metallo-proteases involved with growth and development.
Human Growth Hormone
Human growth hormone (HGH) is prescribed for the treatment of hormone deficiency in children and for wasting disorders in AIDS patients.
HIV Protease with Viracept
HIV protease with the anti-AIDS drug Viracept™ was installed at Pfizer LaJolla, CA in 2002.
Interleukin-5
Interleukin-5 (IL-5) is an interleukin produced to T helper-2 cells and by mast cells. Its functions are to stimulate B cells and to increase antibody secretion.
UDP-N-acetylenolpyruvylglucosamine Reductase
Uridine diphospho-N-acetylenolpyruvyl-glucosamine Reductase (MurB) is a key enzyme in bacterial cell wall biosynthesis.
Nerve Growth Factor
Two sculptures representing nerve growth factor have been built. Both sculptures stand approximately 20 inches above their bases.
Phosopholipase A2
Pancreatic phospholipase A2 is a pancreatic enzyme that releases fatty acids from the second carbon group of glycerol.
Pyrroloquinoline Quinone Synthase
Pyrroloquinoline Quinone (PQQ) is a cofactor found in a class of proteins known as quinoproteins.
Rantes
Chemokine ligand-5 (CCL5) is a protein which in humans is encoded by the CCL5 gene.
Interferon Beta
Rebif is the trademarked name for the Serono drug for the treatment of MS, Interferon beta.
Rubredoxin
Rubredoxin is a low molecular weight bacterial enzyme which mediates one electron transfer reaction.
Subtilisin
The brass and copper model of subtilisin was first built a maquette for a larger piece for the Genencor Corporation.
Thermolysin
Thermolysin is a protease isolated from hot springs.
Trophies
Approximately 50 trophies representing one small and one medium sized protein have been commissioned for presentation at bioCom
Zosyn
ZOSYN/TAZOSYN is an injectable antibiotic formulation composed of the molecules piperacillin and tazosin.
Human Growth Factor Releasing Factor
Human growth hormone (HGH) releasing factor stimulates the synthesis and release of HGH.
Leptin
Leptin is a hormone known as the “satiety hormone”.
RMASDNA
Double stranded DNA.
tRNA
Transfer RNAs (tRNAs) are adaptor molecules that serve as the physical link between the nucleotide sequence of mRNA and the amino acid sequence of proteins.